Interested in trying out a male birth control method?
Participate in a research study.
Help us develop a new
male contraceptive gel.
Contribute to discoveries that may improve health care for you and your family!
Christina Wang, MD
Investigator, The Lundquist Institute
Professor of Medicine, David Geffen School of Medicine at UCLA
Assistant Dean, Clinical and Translational Science, David Geffen School of Medicine at UCLA
Associate Director, UCLA Clinical and Translational Science Institute at The Lundquist Institute at Harbor-UCLA Medical Center
The Lundquist Institute
1124 West Carson Street
Torrance, CA 90502
We're inviting couples to take part in a clinical trial for a male contraceptive gel!
Men who wish to control their fertility currently have limited options. They have to rely on their female partner using contraceptives, use condoms, undergo vasectomy, or abstain.
This study is testing a gel as a possible new method for male family planning. It is a transparent gel applied daily to the skin of the shoulders. It aims to decrease a man’s sperm production in a reversible way without reducing sexual drive. The study also looks at the men’s compliance and the couple’s acceptance of this contraceptive method.
The study product is a combination hormone gel that contains Nestorone® and Testosterone. These hormones suppress the production of sperm to prevent the possibility of fathering a baby. Nestorone has been tested and shown to be safe and blocks the production of male hormones needed to make sperm. The testosterone in the gel works by replacing the testosterone that is normally produced by the body.
The study gel is being developed by The Population Council, a non-profit dedicated to reproductive health, in collaboration with the National Insitute of Health.
There will be no cost to you and your partner for the study medication, study doctor’s time or procedures related to this study. Compensation for your time is provided.
The study will take approximately 2 years. Men will visit the clinic approximately 31 times and their female partner approximately 10 times.
The trial has 3 phases:
Who can participate:
We're looking for couples to participate. Men and their female partners are both active participants in the study and must both consent. See the main criteria for both men and women.
The male partner must:
Be healthy and between 18 and 50 years (inclusive) old.
Be sexually active with the female partner in a stable, mutually monogamous relationship for at least 1 year.
The female partner must:
Be healthy and between 18 and 34 years (inclusive) old.
Be sexually active with the male partner in a stable, mutually monogamous relationship for at least 1 year.
Have regular menstrual cycles of 21-35 days.
Have no known infertility.
Male Partner: You may receive up to $2,985 for your participation.
Female Partner: You may receive up to $1,600 for your participation.
Specific Trial Sites
United States, California
UC Davis Health
Sacramento, California, United States, 95817
Contact: UC Davis OBGYN 916-734-6886 firstname.lastname@example.org
Contact: UC Davis OBGYN 916-734-6846
Principal Investigator: Mitchell Creinin
The Lunquist Institute at Harbor-UCLA Medical Center
Torrance, California, United States, 90509
Contact: Xiaodan Han 310-341-9323 email@example.com
Contact: Elizabeth Ruiz 310-341-9323 firstname.lastname@example.org
Principal Investigator: Christina Wang
United States, Kansas
University of Kansas
Kansas City, Kansas, United States, 66160
United States, Oregon
Oregon Health & Science University
Portland, Oregon, United States, 97239
Contact: Morinne Osborne 503-494-3173 email@example.com
Principal Investigator: Alison Edelman, MD
United States, Pennsylvania
University of Pennsylvania Medical Center
Philadelphia, Pennsylvania, United States, 19104
Contact: Andrea Morley 215-615-4202 firstname.lastname@example.org
Contact: Nicole Clayton 215.615.4202 Nicole.email@example.com
Principal Investigator: Kurt Barnhart, MD, MSCE
United States, Virginia
Eastern Virginia Medical School-EVMS Obstetrics & Gynecology
Norfolk, Virginia, United States, 23507
Contact: Jamie Evans 757-446-7972 evansJL@EVMS.edu
Principal Investigator: David Archer
United States, Washington
University of Washington Medical Center & Health Sciences
Seattle, Washington, United States, 98195
Contact: Stephanie Page, MD, PhD 206-616-1818 firstname.lastname@example.org
Contact: Kathy Winter 206-616-0484 email@example.com
Principal Investigator: Stephanie Page, MD, PhD
Chilean Institute of Reproductive Medicine
Santiago, Chile, 8320000
Contact: Veronica Reyes 56-2-26335887 firstname.lastname@example.org
Contact: Fernanda Pinchetti 562 26328258 email@example.com
Principal Investigator: Gabriela Noe, MS
University of Bologna, Italy
Bologna, Italy, 40138
Contact: Giulia Gava +390512143716 firstname.lastname@example.org
Contact: Silvia Cerpoini +390512143716 email@example.com
Principal Investigator: Cristina Meriggiola
Kenyatta National Hospital
Nairobi, Kenya, 00202
Contact: Sheila Eshiwani 254722799052 firstname.lastname@example.org
Contact: Anne Kaggiah email@example.com
Principal Investigator: John Kinuthia, MBChB, MPH
Contact: Ulrika Fundin 46(8)517 721 28 firstname.lastname@example.org
Contact: Anette Daberius 46(8)-517-721-28 email@example.com
Principal Investigator: Kristina Gemzell-Danielsson, MD
University of Edinburgh
Edinburgh, United Kingdom, EH 16 4SA
Contact: Anne Saunderson 0131 242 2669 A.Saunderson@ed.ac.uk
Contact: Norma Forson 0131 242 2669 firstname.lastname@example.org
Principal Investigator: Richard Anderson, MD, PhD
University of Manchester, UK
Manchester, United Kingdom, M13 9WL
Contact: Verity Natale 0161 276 3296 Verity.Natale@cmft.nhs.uk
Contact: Claudia Grant email@example.com
Principal Investigator: Cheryl Fitzgerald, MD
Men will start applying the gel once every day.
When the man's sperm count drops to an appropriate level to prevent pregnancy, the couple will begin to use the gel as their only form of contraception for one year. The man's sperm count will be checked regularly
Men will stop using the gel and the study team will monitor recovery of sperm count.